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iGenetics: A Molecular Approach – Unlocking the Secrets of Heredity
Introduction:
Have you ever wondered how traits are passed down through generations? How a single cell can develop into a complex organism? The answer lies within the fascinating world of iGenetics, a field that delves into the molecular mechanisms underlying heredity and variation. This in-depth exploration of "iGenetics: A Molecular Approach" will unravel the intricacies of gene expression, regulation, and mutation, providing a comprehensive understanding of this crucial area of biological science. We'll move beyond basic Mendelian genetics, exploring the modern molecular tools and techniques that shape our understanding of inheritance and its implications for health and disease. Prepare to embark on a journey into the very building blocks of life itself.
Understanding the Central Dogma of Molecular Biology
The foundation of iGenetics rests firmly on the central dogma of molecular biology: DNA → RNA → Protein. This seemingly simple flow describes the process by which genetic information encoded in DNA is transcribed into RNA and then translated into proteins, the workhorses of the cell.
DNA: The Blueprint of Life
Deoxyribonucleic acid (DNA) is the molecule that carries the genetic instructions for all living organisms. Its double-helix structure, famously discovered by Watson and Crick, allows for incredibly precise replication and transmission of genetic information. Understanding DNA's structure is key to understanding how genes function and how mutations can arise.
RNA: The Messenger Molecule
Ribonucleic acid (RNA) acts as an intermediary between DNA and protein synthesis. Different types of RNA, including messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), each play crucial roles in this process. mRNA carries the genetic code from DNA to the ribosomes, where protein synthesis takes place.
Protein Synthesis: From Gene to Function
The process of protein synthesis, or translation, involves the decoding of mRNA by ribosomes to assemble amino acids into polypeptide chains, which fold into functional proteins. This intricate process is tightly regulated, ensuring that the right proteins are produced at the right time and in the right amounts.
Gene Expression and Regulation: The Orchestration of Life
While the central dogma provides a basic framework, the reality of gene expression is far more nuanced. Genes are not simply "on" or "off"; their expression is finely tuned through a complex network of regulatory mechanisms.
Transcriptional Regulation: Controlling the Start
Transcriptional regulation controls the rate at which genes are transcribed into mRNA. This involves the interaction of various proteins, including transcription factors, with specific DNA sequences called promoters and enhancers. Understanding these interactions is crucial to understanding how gene expression is controlled in different cells and tissues.
Post-Transcriptional Regulation: Fine-Tuning the Message
Post-transcriptional regulation involves modifying mRNA molecules after transcription. This can include splicing, which removes non-coding regions (introns), and RNA editing, which alters the nucleotide sequence. These processes provide further layers of control over gene expression.
Translational Regulation: Controlling Protein Synthesis
Even after mRNA is produced, the rate of protein synthesis can be regulated. This involves factors that influence the binding of mRNA to ribosomes and the efficiency of translation.
Mutations and Their Impact: The Source of Variation
Mutations are changes in the DNA sequence that can alter the function of genes. These changes can arise spontaneously or be induced by external factors, such as radiation or chemicals.
Types of Mutations
Mutations can range from single nucleotide changes (point mutations) to large-scale chromosomal rearrangements. Point mutations can lead to changes in the amino acid sequence of a protein, while larger mutations can have more drastic effects.
The Significance of Mutations
While many mutations are harmless, some can be detrimental, leading to genetic diseases. Others can be beneficial, providing the raw material for evolution. Understanding the impact of mutations is crucial for both medical and evolutionary biology.
Advanced Techniques in iGenetics: Peering into the Genome
Modern iGenetics relies heavily on advanced molecular techniques to study genes and genomes.
Genome Sequencing: Reading the Book of Life
Genome sequencing allows us to determine the complete DNA sequence of an organism. This powerful technology has revolutionized our understanding of genetics and has applications in medicine, agriculture, and many other fields.
CRISPR-Cas9 Gene Editing: Precisely Modifying the Code
CRISPR-Cas9 is a revolutionary gene-editing technology that allows scientists to make precise changes to the DNA sequence. This technology holds immense potential for treating genetic diseases and engineering organisms with desired traits.
Conclusion:
iGenetics, with its molecular approach, provides a deep and profound understanding of the fundamental principles of heredity. By combining classical genetics with modern molecular techniques, scientists are continually unveiling new insights into the complexities of gene expression, regulation, and mutation. This knowledge is essential for advancing our understanding of human health, disease, and evolution, paving the way for groundbreaking discoveries in medicine, biotechnology, and beyond.
FAQs:
1. What is the difference between classical genetics and iGenetics? Classical genetics focused on observable traits and their inheritance patterns, while iGenetics utilizes molecular techniques to study genes and their expression at the molecular level.
2. How does iGenetics contribute to medicine? iGenetics is crucial for understanding the genetic basis of diseases, developing diagnostic tools, and designing targeted therapies.
3. What are some ethical considerations of iGenetics? Ethical concerns include genetic discrimination, the potential misuse of gene editing technologies, and the social implications of genetic information.
4. How is iGenetics used in agriculture? iGenetics helps improve crop yields, develop disease-resistant plants, and enhance nutritional value.
5. What are some emerging areas of research in iGenetics? Emerging areas include epigenetics (the study of heritable changes in gene expression without changes to the DNA sequence), synthetic biology, and personalized medicine based on individual genomes.
| igenetics a molecular approach: iGenetics: A Molecular Approach Peter J. Russell, 2013-08-29 With its modern chapter organization and new “Focus on Genomics” boxes, iGenetics: A Molecular Approach reflects the increasing molecular emphasis in today’s experimental study of genes while helping students develop problem-solving skills and an appreciation for classic experiments. Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help students to efficiently master genetic concepts. The full text downloaded to your computer With eBooks you can: search for key concepts, words and phrases make highlights and notes as you study share your notes with friends eBooks are downloaded to your computer and accessible either offline through the Bookshelf (available as a free download), available online and also via the iPad and Android apps. Upon purchase, you'll gain instant access to this eBook. Time limit The eBooks products do not have an expiry date. You will continue to access your digital ebook products whilst you have your Bookshelf installed. |
| igenetics a molecular approach: IGenetics Peter J. Russell, 2006 Reflects the dynamic nature of modern genetics by emphasizing an experimental, inquiry-based approach. This text is useful for students who have had some background in biology and chemistry and who are interested in learning the central concepts of genetics. |
| igenetics a molecular approach: IGenetics Peter J. Russell, 2013-07-23 With its modern chapter organization and new Focus on Genomics boxes, iGenetics: A Molecular Approach reflects the increasing molecular emphasis in today's experimental study of genes while helping students develop problem-solving skills and an appreciation for classic experiments. Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening Key Questions and strategically placed Keynotes help students to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help students visualize and understand processes and concepts that are illustrated in the text. |
| igenetics a molecular approach: Studyguide for Igenetics Cram101 Textbook Reviews, Peter J. Russell, 2009-12 Never HIGHLIGHT a Book Again! Virtually all of the testable terms, concepts, persons, places, and events from the textbook are included. Cram101 Just the FACTS101 studyguides give all of the outlines, highlights, notes, and quizzes for your textbook with optional online comprehensive practice tests. Only Cram101 is Textbook Specific. Accompanys: 9780321569769 9780321772886 . |
| igenetics a molecular approach: Outlines and Highlights for Igenetics Cram101 Textbook Reviews, 2009-08 Never HIGHLIGHT a Book Again! Virtually all testable terms, concepts, persons, places, and events are included. Cram101 Textbook Outlines gives all of the outlines, highlights, notes for your textbook with optional online practice tests. Only Cram101 Outlines are Textbook Specific. Cram101 is NOT the Textbook. Accompanys: 9780805346657 |
| igenetics a molecular approach: IGenetics Peter J. Russell, 2010 iGenetics: A Mendelian Approach reflects the dynamic nature of modern genetics by emphasizing an experimental, inquiry-based approach with a solid treatment of many research experiments. 1. Genetics: An Introduction, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of Mendelian Genetic Principles, Quantitative Genetics, Gene Mapping in Eukaryotes, Advanced Gene Mapping in Eukaryotes, Variations in Chromosome Structure and Number, Genetics of Bacteria and Bacteriophages, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription, Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Recombinant DNA Technology, Applications of Recombinant DNA Technology, Genomics, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Non-Mendelian Inheritance, Population Genetics, Molecular Evolution For all readers interested in learning the central concepts of genetics. |
| igenetics a molecular approach: Study Guide and Solutions Manual for IGenetics Peter J. Russell, Bruce A. Chase, 2009-04-17 This student resource, prepared by Bruce Chase of the University of Nebraska, contains chapter outlines of text material, key terms, detailed solutions to all end-of-chapter problems, suggestions for analytical approaches, problem-solving strategies, and 1,000 additional questions for practice and review. Also featured are questions that relate to chapter specific animations and iActivities found on the Genetics Place Website. |
| igenetics a molecular approach: Introduction to Genetics: A Molecular Approach T A Brown, 2012-03-22 Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics. |
| igenetics a molecular approach: Genetics Terence A. Brown, 1998 This introductory text covers all aspects of genetics but adopts a molecular approach, with the gene dealt with first as a chemical structure and then as a Menedelian entity. |
| igenetics a molecular approach: Genetics Peter J. Russell, 1998 Containing updated information on molecular genetics, Peter J. Russell's text emphasises a problem-solving approach that helps students to develop and apply their critical thinking and analysis skills. |
| igenetics a molecular approach: Quantum Adaptivity in Biology: From Genetics to Cognition Masanari Asano, Andrei Khrennikov, Masanori Ohya, Yoshiharu Tanaka, Ichiro Yamato, 2015-04-14 This book examines information processing performed by bio-systems at all scales: from genomes, cells and proteins to cognitive and even social systems. It introduces a theoretical/conceptual principle based on quantum information and non-Kolmogorov probability theory to explain information processing phenomena in biology as a whole. The book begins with an introduction followed by two chapters devoted to fundamentals, one covering classical and quantum probability, which also contains a brief introduction to quantum formalism, and another on an information approach to molecular biology, genetics and epigenetics. It then goes on to examine adaptive dynamics, including applications to biology, and non-Kolmogorov probability theory. Next, the book discusses the possibility to apply the quantum formalism to model biological evolution, especially at the cellular level: genetic and epigenetic evolutions. It also presents a model of the epigenetic cellular evolution based on the mathematical formalism of open quantum systems. The last two chapters of the book explore foundational problems of quantum mechanics and demonstrate the power of usage of positive operator valued measures (POVMs) in biological science. This book will appeal to a diverse group of readers including experts in biology, cognitive science, decision making, sociology, psychology, and physics; mathematicians working on problems of quantum probability and information and researchers in quantum foundations. |
| igenetics a molecular approach: Genetics and Molecular Biology Robert F. Schleif, 1993 In the first edition of Genetics and Molecular Biology, renowned researcher and award-winning teacher Robert Schleif produced a unique and stimulating text that was a notable departure from the standard compendia of facts and observations. Schleif's strategy was to present the underlying fundamental concepts of molecular biology with clear explanations and critical analysis of well-chosen experiments. The result was a concise and practical approach that offered students a real understanding of the subject. This second edition retains that valuable approach--with material thoroughly updated to include an integrated treatment of prokaryotic and eukaryotic molecular biology. Genetics and Molecular Biology is copiously illustrated with two-color line art. Each chapter includes an extensive list of important references to the primary literature, as well as many innovative and thought-provoking problems on material covered in the text or on related topics. These help focus the student's attention of a variety of critical issues. Solutions are provided for half of the problems. Praise for the first edition: Schleif's Genetics and Molecular Biology... is a remarkable achievement. It is an advanced text, derived from material taught largely to postgraduates, and will probably be thought best suited to budding professionals in molecular genetics. In some ways this would be a pity, because there is also gold here for the rest of us... The lessons here in dealing with the information explosion in biology are that an ounce of rationale is worth a pound of facts and that, for educational value, there is nothing to beat an author writing about stuff he knows from theinside.--Nature. Schleif presents a quantitative, chemically rigorous approach to analyzing problems in molecular biology. The text is unique and clearly superior to any currently available.--R.L. Bernstein, San Francisco State University. The greatest strength is the author's ability to challenge the student to become involved and get below the surface.--Clifford Brunk, UCLA |
| igenetics a molecular approach: BRS Biochemistry, Molecular Biology, and Genetics Michael A. Lieberman, Rick Ricer, 2019-01-09 Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Practical, approachable, and perfect for today’s busy medical students and practitioners, BRS Biochemistry, Molecular Biology, and Genetics, Seventh Edition helps ensure excellence in class exams and on the USMLE Step 1. The popular Board Review Series outline format keeps content succinct and accessible for the most efficient review, accompanied by bolded key terms, detailed figures, quick-reference tables, and other aids that highlight important concepts and reinforce understanding. This revised edition is updated to reflect the latest perspectives in biochemistry, molecular biology, and genetics, with a clinical emphasis essential to success in practice. New Clinical Correlation boxes detail the real-world application of chapter concepts, and updated USMLE-style questions with answers test retention and enhance preparation for board exams and beyond. |
| igenetics a molecular approach: Essential Genetics Daniel L. Hartl, Elizabeth W. Jones, 2006 Completely updated to reflect new discoveries and current thinking in the field, the Fourth Edition of Essential Genetics is designed for the shorter, less comprehensive introductory course in genetics. The text is written in a clear, lively, and concise manner and includes many special features that make the book user friendly. Topics were carefully chosen to provide a solid foundation for understanding the basic processes of gene transmission, mutation, expression, and regulation. The text also helps students develop skills in problem solving, achieve a sense of the social and historical context in which genetics has developed, and become aware of the genetic resources and information available through the Internet. |
| igenetics a molecular approach: Study Guide and Solutions Manual Bruce A. Chase, Peter J. Russell, 2005-06 This student resource contains chapter outlines of text material, solutions to all end-of-chapter problems, key terms, suggestions for analytical approaches, problem-solving strategies, and a variety of additional questions for student practice. Also featured are questions that relate to chapter specific animations and iActivities. |
| igenetics a molecular approach: Understanding Genetics Norman V. Rothwell, 1993 Offers a comprehensive and timely introduction to modern genetics. Focusing on the essential aspects of molecular biology, the editor provides a well-written, accessible presentation of the complex field of molecular genetics. |
| igenetics a molecular approach: Karp's Cell Biology Gerald Karp, Janet Iwasa, Wallace Marshall, 2018-01-11 Karp's Cell Biology, Global Edition continues to build on its strength at connecting key concepts to the experiments that reveal how we know what we know in the world of Cell Biology. This classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style to assist students in handling the plethora of details encountered in the Cell Biology course. In this edition, two new co-authors take the helm and help to expand upon the hallmark strengths of the book, improving the student learning experience. |
| igenetics a molecular approach: Lewin's GENES XII Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick, 2017-03-02 Now in its twelfth edition, Lewin's GENES continues to lead with new information and cutting-edge developments, covering gene structure, sequencing, organization, and expression. Leading scientists provide revisions and updates in their individual field of study offering readers current data and information on the rapidly changing subjects in molecular biology. |
| igenetics a molecular approach: Wilson and Walker's Principles and Techniques of Biochemistry and Molecular Biology Keith Wilson, Andreas Hofmann, John M. Walker, Samuel Clokie, 2018-04-19 A major update of a best-selling textbook that introduces students to the key experimental and analytical techniques underpinning life science research. |
| igenetics a molecular approach: Genetics Benjamin A. Pierce, 2013-12-27 With Genetics: A Conceptual Approach, Pierce brings a master teacher's experiences to the introductory genetics textbook, clarifying this complex subject by focusing on the big picture of genetics concepts. The new edition features an emphasis on problem-solving and relevant applications, while incorporating the latest trends in genetics research. |
| igenetics a molecular approach: Visualization of Time-Oriented Data Wolfgang Aigner, Silvia Miksch, Heidrun Schumann, Christian Tominski, 2011-05-30 Time is an exceptional dimension that is common to many application domains such as medicine, engineering, business, or science. Due to the distinct characteristics of time, appropriate visual and analytical methods are required to explore and analyze them. This book starts with an introduction to visualization and historical examples of visual representations. At its core, the book presents and discusses a systematic view of the visualization of time-oriented data along three key questions: what is being visualized (data), why something is visualized (user tasks), and how it is presented (visual representation). To support visual exploration, interaction techniques and analytical methods are required that are discussed in separate chapters. A large part of this book is devoted to a structured survey of 101 different visualization techniques as a reference for scientists conducting related research as well as for practitioners seeking information on how their time-oriented data can best be visualized. |
| igenetics a molecular approach: Principles of Medical Genetics Thomas D. Gelehrter, Francis S. Collins, David Ginsburg, 1998 |
| igenetics a molecular approach: Loose Leaf for Prescott's Microbiology Joanne Willey, Linda Sherwood, Christopher J. Woolverton, 2016-01-07 The author team of Prescott's Microbiology continues the tradition of past editions by providing a balanced, comprehensive introduction to all major areas of microbiology. This balance makes Microbiology appropriate for microbiology majors and mixed majors courses. The authors have introduced a number of pedagogical elements designed to facilitate student learning. They also remain focused on readability, artwork, and the integration of several key themes (including evolution, ecology and diversity) throughout the text, making an already superior text even better. |
| igenetics a molecular approach: Cell Biology, Genetics, Molecular Biology, Evolution and Ecology PS Verma | VK Agarwal, 2004-09 The revised edition of this bestselling textbook provides latest and detailed account of vital topics in biology, namely, Cell Biology, Genetics, Molecular Biology, Evolution and Ecology . The treatment is very exhaustive as the book devotes exclusive parts to each topic, yet in a simple, lucid and concise manner. Simplified and well labelled diagrams and pictures make the subject interesting and easy to understand. It is developed for students of B.Sc. Pass and Honours courses, primarily. However, it is equally useful for students of M.Sc. Zoology, Botany and Biosciences. Aspirants of medical entrance and civil services examinations would also find the book extremely useful. |
| igenetics a molecular approach: Molecular Biotechnology Bernard R. Glick, Jack J. Pasternak, 1998 The second edition explains the principles of recombinant DNA technology as well as other important techniques such as DNA sequencing, the polymerase chain reaction, and the production of monclonal antibodies. |
| igenetics a molecular approach: Introduction to Genetics Terry Brown, 2012 Genetics today is inexorably focused on DNA. The theme of Introduction to Genetics: A Molecular Approach is therefore the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). This progression reflects both the basic logic of life and the way in which modern biological research is structured. The molecular approach is particularly suitable for the large number of students for whom genetics is a part of a broader program in biology, biochemistry, the biomedical sciences, and biotechnology. Introduction to Genetics presents the basic facts and concepts with enough depth of knowledge to stimulate students to move on to more advanced aspects of the subject. The book is divided into three parts. Part 1 examines the function of the gene as a unit of biological information. Part 2 studies the role of the gene as a unit of inheritance. And Part 3 explores some of the areas of research that are responsible for the high profile that genetics has in our modern world, from agriculture and industry to medicine and forensics, and the ethical challenges that genetic knowledge imparts. Introduction to Genetics is available for purchase as an e-book in its entirety or as individual chapters, and as a 1-year or 6-month rental. |
| igenetics a molecular approach: Concepts of Genetics William S. Klug, 2012 Concepts of Genetics is known for its focus on teaching core concepts and problem solving. This best-selling text has been extensively updated, with coverage on emerging topics in genetics, and problem-solving support has been enhanced. |
| igenetics a molecular approach: Genomes 3 Terence A. Brown, 2007 The VitalBook e-book version of Genomes 3 is only available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815341383 Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3is the latest edition of this pioneering textbook. Updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching. Recognizing that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years. |
| igenetics a molecular approach: Introduction to Genomics Arthur Lesk, 2012 This book covers the latest techniques that enable us to study the genome in detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism |
| igenetics a molecular approach: Biology Stephen Wolfe, Peter Russell, Paul Hertz, Cecie Starr, 2007 |
| igenetics a molecular approach: Essential Medical Genetics Michael Connor, Malcolm Ferguson-Smith, 1997-04-29 Essential Medical Genetics gives a balanced introduction to the basic principles of genetics and how it is applied to the understanding and treatment of diseases with a genetic component. Divided into two sections, basic principles and clinical applications, it covers the information that medical students are taught at the preclinical and clinical levels. This book has been written for clinicians, scientists, counselors and teachers--and any other professionals desiring an understanding of modern medical genetics. |
| igenetics a molecular approach: IGenetics:a Molecular Approach : Pearson New International Edition /Forensic Chemistry Peter J. Russell, Suzanne Bell, Andrew R. W. Jackson, Julie M. Jackson, Alan M. Langford, John Dean, Rob Reed, David A. Holmes, Jonathan Weyers, Allan Jones, 2013-08-30 |
| igenetics a molecular approach: Principles of Genetics D. Peter Snustad, 2006 This edition is packed with the lastest developments and information from the labs of current researchers--including the lastest findings from Genomics and RNA Interference.--Jacket |
| igenetics a molecular approach: Madumo, a Man Bewitched Adam Ashforth, 2005-07-08 In a true story of a man bewitched, set against the turbulent backdrop of contemporary Soweto, Ashforth shows that witchcraft is not simply superstition but a complex response to spiritual insecurity in a troubling time of political and economic upheaval. |
| igenetics a molecular approach: BIO2010 National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Committee on Undergraduate Biology Education to Prepare Research Scientists for the 21st Century, 2003-02-13 Biological sciences have been revolutionized, not only in the way research is conductedâ€with the introduction of techniques such as recombinant DNA and digital technologyâ€but also in how research findings are communicated among professionals and to the public. Yet, the undergraduate programs that train biology researchers remain much the same as they were before these fundamental changes came on the scene. This new volume provides a blueprint for bringing undergraduate biology education up to the speed of today's research fast track. It includes recommendations for teaching the next generation of life science investigators, through: Building a strong interdisciplinary curriculum that includes physical science, information technology, and mathematics. Eliminating the administrative and financial barriers to cross-departmental collaboration. Evaluating the impact of medical college admissions testing on undergraduate biology education. Creating early opportunities for independent research. Designing meaningful laboratory experiences into the curriculum. The committee presents a dozen brief case studies of exemplary programs at leading institutions and lists many resources for biology educators. This volume will be important to biology faculty, administrators, practitioners, professional societies, research and education funders, and the biotechnology industry. |
| igenetics a molecular approach: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| igenetics a molecular approach: Essential IGenetics Peter J. Russell, 2003 Building on the proven strength of Russell's step-by-step problem-solving approach, Essential iGenetics blends a classic, Mendel-first approach with modern molecular coverage. This easy-to-read introduction to genetics presents full coverage of the subject in a brief and manageable format. Readers develop and apply critical thinking skills as they work step-by-step through a number of solved genetics problems. Readers can also apply the principles and techniques learned to a variety of problems at the end of each chapter. The book covers basic genetics principles, with balanced coverage of Mendel, historical experiments, and cutting-edge chapters on Genome Analysis and Molecular Evolution. |
| igenetics a molecular approach: Cell And Molecular Biology Peter J. Russell, 2004 |
| igenetics a molecular approach: Thompson & Thompson Genetics in Medicine Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard, 2015-08-16 Updated to reflect the newest changes in genetics, Thompson & Thompson's Genetics in Medicine returns as one of the most favored texts in this fascinating and rapidly evolving field. By integrating the classic principles of human genetics with modern molecular genetics, this medical reference book utilizes a variety of learning tools to help you understand a wide range of genetic disorders. Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics. Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos. |
| igenetics a molecular approach: Junk DNA Nessa Carey, 2015-03-05 From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962. |
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