Chapter 11 Introduction To Genetics

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Chapter 11: Introduction to Genetics – Unraveling the Secrets of Heredity



Have you ever wondered why you have your mother's eyes or your father's smile? The answers lie within the fascinating world of genetics, the study of heredity and variation in living organisms. This comprehensive guide, designed to serve as your ultimate "Chapter 11 Introduction to Genetics" resource, will delve into the fundamental principles of inheritance, exploring the concepts that shape who we are and how life evolves. We'll cover key terminology, fundamental principles, and even touch upon the cutting-edge advancements in this ever-evolving field. Prepare to unlock the secrets of life's blueprint!


Understanding the Basics: Genes, Alleles, and Genotypes



Before diving into complex inheritance patterns, it's crucial to grasp the foundational vocabulary of genetics. Let's start with the gene: the basic unit of heredity, a specific sequence of DNA that codes for a particular trait. These traits can range from eye color and height to susceptibility to certain diseases.

Within a gene, variations exist, called alleles. These are different versions of the same gene, resulting in different expressions of the trait. For example, a gene for eye color might have alleles for brown eyes and blue eyes.

The combination of alleles an individual possesses for a specific gene is known as their genotype. This genotype dictates the observable characteristics, or phenotype. For instance, an individual might have a genotype of two brown eye alleles (homozygous dominant), resulting in a brown eye phenotype.


Mendelian Inheritance: The Foundation of Genetics



Gregor Mendel's experiments with pea plants in the 19th century laid the groundwork for our understanding of inheritance. His work established the principles of Mendelian inheritance, which revolve around the concepts of dominant and recessive alleles.

A dominant allele masks the effect of a recessive allele when both are present. A recessive allele only expresses its phenotype when two copies are present (homozygous recessive). Mendel's laws—the law of segregation and the law of independent assortment—explain how alleles are separated during gamete formation and how different genes are inherited independently.


Beyond Mendel: Exploring More Complex Inheritance Patterns



While Mendel's work provides a solid foundation, many traits are not simply determined by one dominant and one recessive allele. Let's explore some complexities:

#### Incomplete Dominance: A Blend of Traits

In incomplete dominance, neither allele is completely dominant over the other. The heterozygote displays an intermediate phenotype, a blend of the parental traits. A classic example is the snapdragon flower, where a red-flowered plant crossed with a white-flowered plant produces pink-flowered offspring.

#### Codominance: Both Alleles Shine Through

In codominance, both alleles are fully expressed in the heterozygote. A prime example is the ABO blood group system, where individuals with both A and B alleles express both A and B antigens on their red blood cells.

#### Polygenic Inheritance: Traits Shaped by Multiple Genes

Many traits, like height and skin color, are influenced by multiple genes, a phenomenon called polygenic inheritance. This leads to a wide range of phenotypes, rather than distinct categories.


The Role of the Environment: Nature vs. Nurture



It's crucial to remember that genetics isn't the sole determinant of an organism's phenotype. Environmental factors play a significant role. For example, the height of a plant might be genetically determined, but nutrient availability and sunlight exposure will also influence its final height. This highlights the interplay between nature (genetics) and nurture (environment).


Modern Advancements in Genetics



The field of genetics has experienced explosive growth in recent decades. Technologies like the Human Genome Project and CRISPR-Cas9 gene editing have revolutionized our understanding and ability to manipulate genetic material. These advancements hold immense promise for treating genetic diseases and improving human health.


Conclusion



This "Chapter 11 Introduction to Genetics" has provided a foundational understanding of heredity, exploring key concepts from Mendelian inheritance to modern genetic engineering. While this is just a glimpse into this vast field, it provides a solid framework for further exploration. Understanding genetics is essential for comprehending the intricacies of life, disease, and evolution. Further research and study will unlock even more profound insights into the fascinating world of heredity.


Frequently Asked Questions (FAQs)



1. What is the difference between a genotype and a phenotype? A genotype is the genetic makeup of an individual, the combination of alleles they possess. A phenotype is the observable physical or biochemical characteristics determined by the genotype and environmental factors.

2. How can environmental factors influence gene expression? Environmental factors, such as diet, temperature, and exposure to toxins, can alter gene expression by influencing the activity of genes. This can lead to variations in phenotype even among individuals with identical genotypes.

3. What is the significance of the Human Genome Project? The Human Genome Project successfully mapped the entire human genome, providing a comprehensive blueprint of our genetic code. This has revolutionized genetic research, leading to advances in disease diagnosis, treatment, and our understanding of human evolution.

4. What are some ethical considerations related to genetic engineering? Genetic engineering raises ethical concerns about potential misuse, such as genetic discrimination and the creation of "designer babies." Careful consideration of societal implications is crucial as these technologies advance.

5. How can I learn more about genetics? There are many excellent resources available, including introductory biology textbooks, online courses (like Coursera or edX), and scientific journals. You can also explore specialized areas like human genetics, plant genetics, or microbial genetics based on your interests.


  chapter 11 introduction to genetics: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.
  chapter 11 introduction to genetics: Introduction to Conservation Genetics Richard Frankham, Jonathan D. Ballou, David Anthony Briscoe, 2010 This impressive author team brings the wealth of advances in conservation genetics into the new edition of this introductory text, including new chapters on population genomics and genetic issues in introduced and invasive species. They continue the strong learning features for students - main points in the margin, chapter summaries, vital support with the mathematics, and further reading - and now guide the reader to software and databases. Many new references reflect the expansion of this field. With examples from mammals, birds ...
  chapter 11 introduction to genetics: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
  chapter 11 introduction to genetics: An Introduction to Human Molecular Genetics Jack J. Pasternak, 2005-06-14 An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expandsits coverage of the molecular genetics of inherited human diseaseswith the latest research findings and discoveries. Using a unique,systems-based approach, the text offers readers a thoroughexplanation of the gene discovery process and how defective genesare linked to inherited disease states in major organ and tissuesystems. All the latest developments in functional genomics,proteomics, and microarray technology have been thoroughlyincorporated into the text. The first part of the text introduces readers to the fundamentalsof cytogenetics and Mendelian genetics. Next, techniques andstrategies for gene manipulation, mapping, and isolation areexamined. Readers will particularly appreciate the text'sexceptionally thorough and clear explanation of genetic mapping.The final part features unique coverage of the molecular geneticsof distinct biological systems, covering muscle, neurological, eye,cancer, and mitochondrial disorders. Throughout the text, helpfulfigures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text'ssame lucid and engaging style, and will find a wealth of new andexpanded material that brings them fully up to date with a currentunderstanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting,and human population genetics * Expanded and fully revised section on clinical genetics, coveringdiagnostic testing, molecular screening, and varioustreatments This text is targeted at upper-level undergraduate students,graduate students, and medical students. It is also an excellentreference for researchers and physicians who need a clinicallyrelevant reference for the molecular genetics of inherited humandiseases.
  chapter 11 introduction to genetics: Introducing Genetics Alison Thomas, 2014-12-18 Like its predecessor, the new edition of Introducing Genetics is an accessible introduction to genetics from first principles to recent developments. It covers the three key areas of genetics: Mendelian, molecular and population and will be easily understood by first and foundation year students in the biological sciences.
  chapter 11 introduction to genetics: The Neurobiological Basis of Suicide Yogesh Dwivedi, 2012-06-25 With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
  chapter 11 introduction to genetics: C. Elegans II Donald L. Riddle, 1997 Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
  chapter 11 introduction to genetics: Molecular Biology of the Cell , 2002
  chapter 11 introduction to genetics: Introduction to Psychology Jennifer Walinga, Charles Stangor, This book is designed to help students organize their thinking about psychology at a conceptual level. The focus on behaviour and empiricism has produced a text that is better organized, has fewer chapters, and is somewhat shorter than many of the leading books. The beginning of each section includes learning objectives; throughout the body of each section are key terms in bold followed by their definitions in italics; key takeaways, and exercises and critical thinking activities end each section.
  chapter 11 introduction to genetics: Principles of Plant Genetics and Breeding George Acquaah, 2020-12-14 The revised edition of the bestselling textbook, covering both classical and molecular plant breeding Principles of Plant Genetics and Breeding integrates theory and practice to provide an insightful examination of the fundamental principles and advanced techniques of modern plant breeding. Combining both classical and molecular tools, this comprehensive textbook describes the multidisciplinary strategies used to produce new varieties of crops and plants, particularly in response to the increasing demands to of growing populations. Illustrated chapters cover a wide range of topics, including plant reproductive systems, germplasm for breeding, molecular breeding, the common objectives of plant breeders, marketing and societal issues, and more. Now in its third edition, this essential textbook contains extensively revised content that reflects recent advances and current practices. Substantial updates have been made to its molecular genetics and breeding sections, including discussions of new breeding techniques such as zinc finger nuclease, oligonucleotide directed mutagenesis, RNA-dependent DNA methylation, reverse breeding, genome editing, and others. A new table enables efficient comparison of an expanded list of molecular markers, including Allozyme, RFLPs, RAPD, SSR, ISSR, DAMD, AFLP, SNPs and ESTs. Also, new and updated “Industry Highlights” sections provide examples of the practical application of plant breeding methods to real-world problems. This new edition: Organizes topics to reflect the stages of an actual breeding project Incorporates the most recent technologies in the field, such as CRSPR genome edition and grafting on GM stock Includes numerous illustrations and end-of-chapter self-assessment questions, key references, suggested readings, and links to relevant websites Features a companion website containing additional artwork and instructor resources Principles of Plant Genetics and Breeding offers researchers and professionals an invaluable resource and remains the ideal textbook for advanced undergraduates and graduates in plant science, particularly those studying plant breeding, biotechnology, and genetics.
  chapter 11 introduction to genetics: Sexual Reproduction in Animals and Plants Hitoshi Sawada, Naokazu Inoue, Megumi Iwano, 2014-02-07 This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.
  chapter 11 introduction to genetics: Landscape Genetics Niko Balkenhol, Samuel Cushman, Andrew Storfer, Lisette Waits, 2015-11-09 LANDSCAPE GENETICS: CONCEPTS, METHODS, APPLICATIONS LANDSCAPE GENETICS: CONCEPTS, METHODS, APPLICATIONS Edited by Niko Balkenhol, Samuel A. Cushman, Andrew T. Storfer, Lisette P. Waits Landscape genetics is an exciting and rapidly growing field, melding methods and theory from landscape ecology and population genetics to address some of the most challenging and urgent ecological and evolutionary topics of our time. Landscape genetic approaches now enable researchers to study in detail how environmental complexity in space and time affect gene flow, genetic drift, and local adaptation. However, learning about the concepts and methods underlying the field remains challenging due to the highly interdisciplinary nature of the field, which relies on topics that have traditionally been treated separately in classes and textbooks. In this edited volume, some of the leading experts in landscape genetics provide the first comprehensive introduction to underlying concepts, commonly used methods, and current and future applications of landscape genetics. Consistent with the interdisciplinary nature of the field, the book includes textbook-like chapters that synthesize fundamental concepts and methods underlying landscape genetics (Part 1), chapters on advanced topics that deserve a more in-depth treatment (Part 2), and chapters illustrating the use of concepts and methods in empirical applications (Part 3). Aimed at beginning landscape geneticists and experienced researchers alike, this book will be helpful for all scientists and practitioners interested in learning, teaching, and applying landscape genetics.
  chapter 11 introduction to genetics: Guide to Research Techniques in Neuroscience Matt Carter, Rachel Essner, Nitsan Goldstein, Manasi Iyer, 2022-03-26 Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - Walk-through boxes that guide readers through experiments step-by-step
  chapter 11 introduction to genetics: Introduction to Genetic Algorithms S.N. Sivanandam, S. N. Deepa, 2007-10-24 This book offers a basic introduction to genetic algorithms. It provides a detailed explanation of genetic algorithm concepts and examines numerous genetic algorithm optimization problems. In addition, the book presents implementation of optimization problems using C and C++ as well as simulated solutions for genetic algorithm problems using MATLAB 7.0. It also includes application case studies on genetic algorithms in emerging fields.
  chapter 11 introduction to genetics: An Introduction to Genetic Statistics Oscar Kempthorne, 1957 Elementary probability; Random mating populations; Elementary selection problems; The elementary stochastic theory of genetic populations; Inbreeding; The generation matrix theory of inbreeding; Tests of genetic hypotheses; The estimation of genetic parameters; The planning of experiments; Statistical problems in human genetics; The analysis of variation; The partition of variance; Multiple regression, correlation and adjustment of data, and path analysis; Inheritance of quantitative characters in a random mating population; Non-random mating deploid populations with one locus segregating; Correlation between relatives under inbreeding with one locus segregating; One-locus polyploid populations; Diploid populations with arbitrary number of segregating loci and arbitrary epistacy; Inbreeding with a arbitrary diploid population; Population derived from inbred lines; Infinitesimal equilibrium theory of assortative mating; Selection for quantitative characters.
  chapter 11 introduction to genetics: An Introduction to Genetics for Language Scientists Dan Dediu, 2015-03-12 An introduction to genetics aimed at language scientists, with carefully selected concepts, methods and findings exploring language and speech.
  chapter 11 introduction to genetics: Mapping and Sequencing the Human Genome National Research Council, Division on Earth and Life Studies, Commission on Life Sciences, Committee on Mapping and Sequencing the Human Genome, 1988-01-01 There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
  chapter 11 introduction to genetics: Introduction to Forest Genetics Jonathan Wright, 2012-12-02 Introduction to Forest Genetics examines some of the basic genetic concepts typically used in forestry and tree improvement studies, including Mendelian and population genetics. It also describes techniques that are generally useful in tree improvement work, including individual tree selection and breeding, provenance testing, species and racial hybridization, and introduction of exotics. Organized into 19 chapters, this volume begins with an overview of forest genetics and problems associated with forest genetics. It then discusses concepts from basic genetics, including chromosome structure and function; DNA and RNA; nongenetic inheritance; and genotype versus phenotype. Other chapters focus on inbreeding: complete elimination of homozygous recessive trees; mutation and migration; and controlled pollination and vegetative propagation. The book also covers the establishment and measurement of test plantations; general principles and methods of selective breeding; choice of breeding method and type of seed orchard; heritability and genetic gain; geographic variation in Scotch pine and American trees; species and racial hybridization; chromosome studies; and polyploidy and haploidy breeding. This book is a valuable resource for foresters, professional tree breeders, and those with or without previous training in genetics or forestry.
  chapter 11 introduction to genetics: An Introduction to Genetic Engineering Desmond S. T. Nicholl, 2002-02-07 The author presents a basic introduction to the world of genetic engineering. Copyright © Libri GmbH. All rights reserved.
  chapter 11 introduction to genetics: Experiments in Plant Hybridisation Gregor Mendel, 2008-11-01 Experiments which in previous years were made with ornamental plants have already afforded evidence that the hybrids, as a rule, are not exactly intermediate between the parental species. With some of the more striking characters, those, for instance, which relate to the form and size of the leaves, the pubescence of the several parts, etc., the intermediate, indeed, is nearly always to be seen; in other cases, however, one of the two parental characters is so preponderant that it is difficult, or quite impossible, to detect the other in the hybrid. from 4. The Forms of the Hybrid One of the most influential and important scientific works ever written, the 1865 paper Experiments in Plant Hybridisation was all but ignored in its day, and its author, Austrian priest and scientist GREGOR JOHANN MENDEL (18221884), died before seeing the dramatic long-term impact of his work, which was rediscovered at the turn of the 20th century and is now considered foundational to modern genetics. A simple, eloquent description of his 18561863 study of the inheritance of traits in pea plantsMendel analyzed 29,000 of themthis is essential reading for biology students and readers of science history. Cosimo presents this compact edition from the 1909 translation by British geneticist WILLIAM BATESON (18611926).
  chapter 11 introduction to genetics: A History of Genetics Alfred Henry Sturtevant, 2001 In the small “Fly Room†at Columbia University, T.H. Morgan and his students, A.H. Sturtevant, C.B. Bridges, and H.J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written in 1965 by one of those present at the beginning. His account is one of the few authoritative, analytic works on the early history of genetics. This attractive reprint is accompanied by a website, http://www.esp.org/books/sturt/history/ offering full-text versions of the key papers discussed in the book, including the world's first genetic map.
  chapter 11 introduction to genetics: Introduction to Genetics: A Molecular Approach T A Brown, 2012-03-22 Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics.
  chapter 11 introduction to genetics: An Introduction to Genetic Algorithms Melanie Mitchell, 1998-03-02 Genetic algorithms have been used in science and engineering as adaptive algorithms for solving practical problems and as computational models of natural evolutionary systems. This brief, accessible introduction describes some of the most interesting research in the field and also enables readers to implement and experiment with genetic algorithms on their own. It focuses in depth on a small set of important and interesting topics—particularly in machine learning, scientific modeling, and artificial life—and reviews a broad span of research, including the work of Mitchell and her colleagues. The descriptions of applications and modeling projects stretch beyond the strict boundaries of computer science to include dynamical systems theory, game theory, molecular biology, ecology, evolutionary biology, and population genetics, underscoring the exciting general purpose nature of genetic algorithms as search methods that can be employed across disciplines. An Introduction to Genetic Algorithms is accessible to students and researchers in any scientific discipline. It includes many thought and computer exercises that build on and reinforce the reader's understanding of the text. The first chapter introduces genetic algorithms and their terminology and describes two provocative applications in detail. The second and third chapters look at the use of genetic algorithms in machine learning (computer programs, data analysis and prediction, neural networks) and in scientific models (interactions among learning, evolution, and culture; sexual selection; ecosystems; evolutionary activity). Several approaches to the theory of genetic algorithms are discussed in depth in the fourth chapter. The fifth chapter takes up implementation, and the last chapter poses some currently unanswered questions and surveys prospects for the future of evolutionary computation.
  chapter 11 introduction to genetics: An Introduction to Modern Genetics C H (Conrad Hal) 1905- Waddington, 2023-07-22 C.H. Waddington, one of the most prominent geneticists of the twentieth century, provides a clear and concise overview of modern genetics in this landmark book. From DNA to epigenetics, Waddington covers the full breadth of the field, making this an essential read for students and professionals in genetics and related fields. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
  chapter 11 introduction to genetics: Equine Color Genetics D. Phillip Sponenberg, Rebecca Bellone, 2017-05-30 Equine Color Genetics, Fourth Edition presents a detailed examination of the color variation in horses and donkeys and the genetic mechanisms that produce color variations. Thoroughly covers the basic colors in horses, including bay, chestnut, black, and brown Details the genetic basis of the colors built from the basic coat color, including dilutions and white patterning Provides an explanation of genetic mechanisms that determine coat color Presents a thorough revision and update, including new advances in molecular genetics, biochemistry, molecular mechanisms, genetic loci, coat colors before domestication, and more Offers a new introduction describing the principles of genetics and genomics research to help outline how knowledge is discovered and to assist the reader in understanding concepts covered in the book
  chapter 11 introduction to genetics: Introduction to Genomics Arthur Lesk, 2012 This book covers the latest techniques that enable us to study the genome in detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism
  chapter 11 introduction to genetics: The Genetic Landscape of Diabetes Laura Dean, J. R. McEntyre, National Center for Biotechnology Information (U.S.), National Institute of Diabetes and Digestive and Kidney Diseases (U.S.), 2004
  chapter 11 introduction to genetics: Introduction to Conservation Genetics Richard Frankham, Jonathan D. Ballou, David A. Briscoe, 2010-01-28 This impressive author team brings the wealth of advances in conservation genetics into the new edition of this introductory text, including new chapters on population genomics and genetic issues in introduced and invasive species. They continue the strong learning features for students - main points in the margin, chapter summaries, vital support with the mathematics, and further reading - and now guide the reader to software and databases. Many new references reflect the expansion of this field. With examples from mammals, birds, reptiles, fish, amphibians, plants and invertebrates, this is an ideal introduction to conservation genetics for a broad audience. The text tackles the quantitative aspects of conservation genetics, and has a host of pedagogy to support students learning the numerical side of the subject. Combined with being up-to-date, its user-friendly writing style and first-class illustration programme forms a robust teaching package.
  chapter 11 introduction to genetics: A Primer of Conservation Genetics Richard Frankham, Jonathan D. Ballou, David A. Briscoe, 2004-02-12 This concise, entry level text provides an introduction to the importance of genetic studies in conservation and presents the essentials of the discipline in an easy-to-follow format, with main points and terms clearly highlighted. The authors assume only a basic knowledge of Mendelian genetics and simple statistics, making the book accessible to those with a limited background in these areas. Connections between conservation genetics and the wider field of conservation biology are interwoven throughout the book. Worked examples are provided throughout to help illustrate key equations and glossary and suggestions for further reading provide additional support for the reader. Many beautiful pen and ink portraits of endangered species are included to enhance the text. Written for short, introductory level courses in genetics, conservation genetics and conservation biology, this book will also be suitable for practising conservation biologists, zoo biologists and wildlife managers.
  chapter 11 introduction to genetics: Reverse Genetics of RNA Viruses Anne Bridgen, 2012-10-07 Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
  chapter 11 introduction to genetics: Handbook of Statistical Genetics David J. Balding, Martin Bishop, Chris Cannings, 2008-06-10 The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.
  chapter 11 introduction to genetics: Bioinformatics for Geneticists Michael R. Barnes, Ian C. Gray, 2003-07-01 This timely book illustrates the value of bioinformatics, not simply as a set of tools but rather as a science increasingly essential to navigate and manage the host of information generated by genomics and the availability of completely sequenced genomes. Bioinformatics can be used at all stages of genetics research: to improve study design, to assist in candidate gene identification, to aid data interpretation and management and to shed light on the molecular pathology of disease-causing mutations. Written specifically for geneticists, this book explains the relevance of bioinformatics showing how it may be used to enhance genetic data mining and markedly improve genetic analysis.
  chapter 11 introduction to genetics: Bee Genetics and Breeding Thomas E. Rinderer, 2013-09-03 Bee Genetics and Breeding provides an overview of the state of knowledge in bee genetics and breeding. The book is organized into two parts. Part I deals with the scholarly issues of bee genetics. It is intended as a reference source for students of both bees and genetics. It could also serve as a text for university courses in bee genetics. Topics discussed include the evolution of eusocial insects; geographical variability and classification of honey bees; and behavioral and biochemical genetics of honey bees. Part II deals more specifically with the practical issues of bee breeding. The discussions include the quantitative genetics of honey bees; ways to define and measure honey-bee characteristics so that the best parents for honey-bee stock improvement programs can be selected; and mating designs. This section contains sufficient guidance for bee breeders to initiate or improve breeding programs. Apiculturalists generally will find this part especially interesting since the quality of their own bee stock depends on the skills and knowledge of the breeders who produce their queens.
  chapter 11 introduction to genetics: The Selfish Gene Richard Dawkins, 1989 Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
  chapter 11 introduction to genetics: Molecular Evolutionary Genetics Masatoshi Nei, 1987 -- The Scientist
  chapter 11 introduction to genetics: Mendelian Randomization Stephen Burgess, Simon G. Thompson, 2015-03-06 Presents the Terminology and Methods of Mendelian Randomization for Epidemiological StudiesMendelian randomization uses genetic instrumental variables to make inferences about causal effects based on observational data. It, therefore, can be a reliable way of assessing the causal nature of risk factors, such as biomarkers, for a wide range of disea
  chapter 11 introduction to genetics: Fundamentals of Forensic DNA Typing John M. Butler, 2009-09-30 Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- Data, Notes & Applications sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
  chapter 11 introduction to genetics: Governing Agrobiodiversity Dr Regine Andersen, 2013-03-28 Plant genetic diversity is crucial to the breeding of food crops and is therefore a central precondition for food security. Diverse genetic resources provide the genetic traits required to deal with crop pests and diseases, as well as changing climate conditions. Plant genetic diversity is also essential for traditional small-scale farming, and is therefore an indispensable factor in the fight against poverty. However, the diversity of domesticated plant varieties is disappearing at an alarming rate while interest in the commercial use of genetic resources has increased in line with bio-technologies, followed by demands for intellectual property rights. This important book contributes to our understanding of how international regimes affect the management of plant genetic resources for food and agriculture in developing countries. It identifies entry points to shape a better governance of agrobiodiversity and provides the first comprehensive analysis of how the international agreements pertaining to crop genetic resources affect the management of these vital resources for food security and poverty eradication in developing countries.
  chapter 11 introduction to genetics: Biometrical genetics Kenneth Mather, John L. Jinks, 2013-11-11 The properties of continuous variation are basic to the theory of evolution and to the practice of plant and animal improvement. Yet the genetical study of continuous variation has lagged far behind that of discontinuous variation. The reason for this situation is basically methodological. Mendel gave us not merely his principles of heredity, but also a method of experiment by which these principles could be tested over a wider range of living species, and extended into the elaborate genetical theory of today. The power of this tool is well attested by the speed with which genetics has grown. In less than fifty years, it has not only developed a theoretical structure which is unique in the biological sciences, but has established a union with nuclear cytology so close that the two have become virtually a single science offering us a new approach to problems so diverse as those of evolution, development, disease, cellular chemistry and human welfare. Much of this progress would have been impossible and all would have been slower without the Mendelian method of recognizing and using unit differences in the genetic materials.
  chapter 11 introduction to genetics: Problems and Solutions for Strachan and Read's Human Molecular Genetics 2 David James Matthes, Andrew Read, 2001
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