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Cell Cycle Regulation POGIL: Mastering the Intricacies of Cell Division
Introduction:
Understanding the cell cycle is fundamental to comprehending biology, and the POGIL (Process Oriented Guided Inquiry Learning) activities offer a powerful approach to mastering this complex topic. This comprehensive guide delves into the intricacies of cell cycle regulation using the POGIL framework. We'll explore the key checkpoints, regulatory molecules (like cyclins and CDKs), and the consequences of dysregulation, all within the context of effective POGIL activities. Whether you're a student struggling to grasp the concepts or an educator looking for engaging teaching resources, this post provides valuable insights and strategies for navigating the world of cell cycle regulation through POGIL.
Understanding the Cell Cycle: A Foundation for POGIL Activities
The cell cycle is a tightly regulated process essential for growth, repair, and reproduction in all living organisms. It's a continuous cycle encompassing several distinct phases:
G1 (Gap 1): The cell grows in size, synthesizes proteins, and prepares for DNA replication.
S (Synthesis): DNA replication occurs, doubling the genetic material.
G2 (Gap 2): The cell continues to grow and prepares for mitosis.
M (Mitosis): The cell divides its duplicated chromosomes and cytoplasm, resulting in two daughter cells.
The Importance of Cell Cycle Checkpoints
The cell cycle isn't a simple linear progression. It's punctuated by checkpoints, crucial control points that ensure the accuracy and integrity of each phase. These checkpoints monitor various factors, including:
DNA integrity: Is the DNA replicated correctly? Are there any damages that need repair?
Cell size: Is the cell large enough to divide successfully?
Environmental conditions: Are the external conditions favorable for cell division?
These checkpoints prevent errors and ensure that only healthy cells proceed to the next phase, thus maintaining genomic stability.
Key Regulatory Molecules: Cyclins and Cyclin-Dependent Kinases (CDKs)
The cell cycle is primarily regulated by two classes of proteins: cyclins and cyclin-dependent kinases (CDKs). Cyclins are regulatory proteins whose concentrations fluctuate throughout the cell cycle. CDKs are enzymes that phosphorylate target proteins, driving the cell cycle forward. The complex formation between cyclins and CDKs is crucial for activating CDK's enzymatic activity. Different cyclin-CDK complexes govern different phases of the cell cycle.
The Role of Cyclins and CDKs at Checkpoints
Cyclin-CDK complexes are key players at cell cycle checkpoints. They integrate signals from various pathways to decide whether to proceed or halt the cycle. For example, a deficiency in DNA replication or damage will trigger signaling cascades that inhibit cyclin-CDK activity, preventing the cell from entering mitosis prematurely.
Applying POGIL to Cell Cycle Regulation
POGIL activities provide a student-centered approach to learning. Instead of passively receiving information, students actively engage in collaborative problem-solving. For cell cycle regulation, POGIL activities can focus on:
Modeling the cell cycle: Students can create diagrams or models to illustrate the different phases and regulatory mechanisms.
Analyzing experimental data: Students can interpret data from experiments investigating cell cycle checkpoints or the effects of various mutations.
Designing experiments: Students can design experiments to test hypotheses related to cell cycle regulation.
Solving problems: Students can tackle problems that require them to apply their understanding of cell cycle regulation to novel scenarios.
Effective Strategies for POGIL Activities on Cell Cycle Regulation
Start with a clear learning objective: Define what students should understand by the end of the activity.
Provide relevant background information: Ensure students have a foundational understanding of the basic concepts.
Facilitate collaboration: Encourage students to discuss their ideas and learn from each other.
Provide appropriate guidance: Offer support and clarification when needed, but avoid providing answers directly.
Assess understanding: Use formative assessment techniques to gauge student learning.
Consequences of Cell Cycle Dysregulation
Errors in cell cycle regulation can have severe consequences, leading to uncontrolled cell growth and potentially cancer. Mutations in genes encoding cyclins, CDKs, or checkpoint proteins can disrupt the normal cell cycle progression, resulting in the formation of tumors.
Conclusion
Mastering cell cycle regulation requires a deep understanding of its intricate mechanisms. POGIL activities provide a powerful and engaging framework for students to actively construct this knowledge. By actively participating in collaborative problem-solving, students develop a more robust understanding of cell cycle control, the importance of checkpoints, and the serious consequences of dysregulation. Through effective POGIL implementation and the use of various learning strategies, students can confidently navigate the complexities of this crucial biological process.
FAQs:
1. What are some examples of POGIL activities for cell cycle regulation? Activities can involve analyzing graphs of cyclin levels, interpreting data from experiments inhibiting specific cell cycle regulators, designing experiments to test the effects of a drug on cell cycle progression, or creating models illustrating the interactions between cyclins and CDKs.
2. How can I adapt POGIL activities for different learning styles? Provide a variety of activities to cater to different learning preferences. Some students may benefit from visual aids, while others might prefer hands-on experiments or group discussions.
3. What are the common misconceptions students have about cell cycle regulation? Common misconceptions include believing the cell cycle is a simple linear process, underestimating the importance of checkpoints, or misunderstanding the roles of cyclins and CDKs.
4. How can I assess student learning after a POGIL activity on cell cycle regulation? Use a variety of assessment methods, including short answer questions, problem-solving tasks, and group presentations.
5. Where can I find more resources for developing POGIL activities on cell cycle regulation? The POGIL Project website offers numerous resources and examples of POGIL activities. Additionally, scientific literature and textbooks can provide information and data for developing context-rich problems.
| cell cycle regulation pogil: Biology for AP ® Courses Julianne Zedalis, John Eggebrecht, 2017-10-16 Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences. |
| cell cycle regulation pogil: The Eukaryotic Cell Cycle J. A. Bryant, Dennis Francis, 2008 Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers. It discusses important experiments, organisms of interest and research findings connected to the different stages of the cycle and the components involved. |
| cell cycle regulation pogil: Cell Cycle Regulation Philipp Kaldis, 2006-06-26 This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer. |
| cell cycle regulation pogil: Concepts of Biology Samantha Fowler, Rebecca Roush, James Wise, 2023-05-12 Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy. |
| cell cycle regulation pogil: Anatomy and Physiology J. Gordon Betts, Peter DeSaix, Jody E. Johnson, Oksana Korol, Dean H. Kruse, Brandon Poe, James A. Wise, Mark Womble, Kelly A. Young, 2013-04-25 |
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| cell cycle regulation pogil: The Cell Cycle and Cancer Renato Baserga, 1971 |
| cell cycle regulation pogil: The Plant Cell Cycle Dirk Inzé, 2011-06-27 In recent years, the study of the plant cell cycle has become of major interest, not only to scientists working on cell division sensu strictu , but also to scientists dealing with plant hormones, development and environmental effects on growth. The book The Plant Cell Cycle is a very timely contribution to this exploding field. Outstanding contributors reviewed, not only knowledge on the most important classes of cell cycle regulators, but also summarized the various processes in which cell cycle control plays a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists. |
| cell cycle regulation pogil: Basic Concepts in Biochemistry: A Student's Survival Guide Hiram F. Gilbert, 2000 Basic Concepts in Biochemistry has just one goal: to review the toughest concepts in biochemistry in an accessible format so your understanding is through and complete.--BOOK JACKET. |
| cell cycle regulation pogil: Preparing for the Biology AP Exam Neil A. Campbell, Jane B. Reece, Fred W. Holtzclaw, Theresa Knapp Holtzclaw, 2009-11-03 Fred and Theresa Holtzclaw bring over 40 years of AP Biology teaching experience to this student manual. Drawing on their rich experience as readers and faculty consultants to the College Board and their participation on the AP Test Development Committee, the Holtzclaws have designed their resource to help your students prepare for the AP Exam. Completely revised to match the new 8th edition of Biology by Campbell and Reece. New Must Know sections in each chapter focus student attention on major concepts. Study tips, information organization ideas and misconception warnings are interwoven throughout. New section reviewing the 12 required AP labs. Sample practice exams. The secret to success on the AP Biology exam is to understand what you must know and these experienced AP teachers will guide your students toward top scores! |
| cell cycle regulation pogil: Teaching at Its Best Linda B. Nilson, 2010-04-20 Teaching at Its Best This third edition of the best-selling handbook offers faculty at all levels an essential toolbox of hundreds of practical teaching techniques, formats, classroom activities, and exercises, all of which can be implemented immediately. This thoroughly revised edition includes the newest portrait of the Millennial student; current research from cognitive psychology; a focus on outcomes maps; the latest legal options on copyright issues; and how to best use new technology including wikis, blogs, podcasts, vodcasts, and clickers. Entirely new chapters include subjects such as matching teaching methods with learning outcomes, inquiry-guided learning, and using visuals to teach, and new sections address Felder and Silverman's Index of Learning Styles, SCALE-UP classrooms, multiple true-false test items, and much more. Praise for the Third Edition of Teaching at Its BestEveryone veterans as well as novices will profit from reading Teaching at Its Best, for it provides both theory and practical suggestions for handling all of the problems one encounters in teaching classes varying in size, ability, and motivation. Wilbert McKeachie, Department of Psychology, University of Michigan, and coauthor, McKeachie's Teaching TipsThis new edition of Dr. Nilson's book, with its completely updated material and several new topics, is an even more powerful collection of ideas and tools than the last. What a great resource, especially for beginning teachers but also for us veterans! L. Dee Fink, author, Creating Significant Learning ExperiencesThis third edition of Teaching at Its Best is successful at weaving the latest research on teaching and learning into what was already a thorough exploration of each topic. New information on how we learn, how students develop, and innovations in instructional strategies complement the solid foundation established in the first two editions. Marilla D. Svinicki, Department of Psychology, The University of Texas, Austin, and coauthor, McKeachie's Teaching Tips |
| cell cycle regulation pogil: Teaching and Learning STEM Richard M. Felder, Rebecca Brent, 2024-03-19 The widely used STEM education book, updated Teaching and Learning STEM: A Practical Guide covers teaching and learning issues unique to teaching in the science, technology, engineering, and math (STEM) disciplines. Secondary and postsecondary instructors in STEM areas need to master specific skills, such as teaching problem-solving, which are not regularly addressed in other teaching and learning books. This book fills the gap, addressing, topics like learning objectives, course design, choosing a text, effective instruction, active learning, teaching with technology, and assessment—all from a STEM perspective. You’ll also gain the knowledge to implement learner-centered instruction, which has been shown to improve learning outcomes across disciplines. For this edition, chapters have been updated to reflect recent cognitive science and empirical educational research findings that inform STEM pedagogy. You’ll also find a new section on actively engaging students in synchronous and asynchronous online courses, and content has been substantially revised to reflect recent developments in instructional technology and online course development and delivery. Plan and deliver lessons that actively engage students—in person or online Assess students’ progress and help ensure retention of all concepts learned Help students develop skills in problem-solving, self-directed learning, critical thinking, teamwork, and communication Meet the learning needs of STEM students with diverse backgrounds and identities The strategies presented in Teaching and Learning STEM don’t require revolutionary time-intensive changes in your teaching, but rather a gradual integration of traditional and new methods. The result will be a marked improvement in your teaching and your students’ learning. |
| cell cycle regulation pogil: Pulmonary Gas Exchange G. Kim Prisk, Susan R. Hopkins, 2013-08-01 The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process. |
| cell cycle regulation pogil: Anatomy & Physiology Lindsay Biga, Devon Quick, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Matern, Katie Morrison-Graham, Jon Runyeon, 2019-09-26 A version of the OpenStax text |
| cell cycle regulation pogil: Principles of Biology Lisa Bartee, Walter Shiner, Catherine Creech, 2017 The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research. |
| cell cycle regulation pogil: Cell Cycle Checkpoint Control Protocols Howard B. Lieberman, 2008-02-02 The field of cell cycle regulation is based on the observation that the life cycle of a cell progresses through several distinct phases, G1, M, S, and G2, occurring in a well-defined temporal order. Details of the mechanisms involved are rapidly emerging and appear extraordinarily complex. Furthermore, not only is the order of the phases important, but in normal eukaryotic cells one phase will not begin unless the prior phase is completed successfully. Che- point control mechanisms are essentially surveillance systems that monitor the events in each phase, and assure that the cell does not progress prematurely to the next phase. If conditions are such that the cell is not ready to progress—for example, because of incomplete DNA replication in S or DNA damage that may interfere with chromosome segregation in M—a transient delay in cell cycle progression will occur. Once the inducing event is properly handled— for example, DNA replication is no longer blocked or damaged DNA is repaired—cell cycle progression continues. Checkpoint controls have recently been the focus of intense study by investigators interested in mechanisms that regulate the cell cycle. Furthermore, the relationship between checkpoint c- trol and carcinogenesis has additionally enhanced interest in these cell cycle regulatory pathways. It is clear that cancer cells often lack these checkpoints and exhibit genomic instability as a result. Moreover, several tumor suppressor genes participate in checkpoint control, and alterations in these genes are as- ciated with genomic instability as well as the development of cancer. |
| cell cycle regulation pogil: The Art of Changing the Brain James E. Zull, 2023-07-03 Neuroscience tells us that the products of the mind--thought, emotions, artistic creation--are the result of the interactions of the biological brain with our senses and the physical world: in short, that thinking and learning are the products of a biological process.This realization, that learning actually alters the brain by changing the number and strength of synapses, offers a powerful foundation for rethinking teaching practice and one's philosophy of teaching.James Zull invites teachers in higher education or any other setting to accompany him in his exploration of what scientists can tell us about the brain and to discover how this knowledge can influence the practice of teaching. He describes the brain in clear non-technical language and an engaging conversational tone, highlighting its functions and parts and how they interact, and always relating them to the real world of the classroom and his own evolution as a teacher. The Art of Changing the Brain is grounded in the practicalities and challenges of creating effective opportunities for deep and lasting learning, and of dealing with students as unique learners. |
| cell cycle regulation pogil: Microbiology Nina Parker, OpenStax, Mark Schneegurt, AnhHue Thi Tu, Brian M. Forster, Philip Lister, 2016-05-30 Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.--BC Campus website. |
| cell cycle regulation pogil: ICOPE 2020 Ryzal Perdana, Gede Eka Putrawan, Sunyono, 2021-03-24 We are delighted to introduce the Proceedings of the Second International Conference on Progressive Education (ICOPE) 2020 hosted by the Faculty of Teacher Training and Education, Universitas Lampung, Indonesia, in the heart of the city Bandar Lampung on 16 and 17 October 2020. Due to the COVID-19 pandemic, we took a model of an online organised event via Zoom. The theme of the 2nd ICOPE 2020 was “Exploring the New Era of Education”, with various related topics including Science Education, Technology and Learning Innovation, Social and Humanities Education, Education Management, Early Childhood Education, Primary Education, Teacher Professional Development, Curriculum and Instructions, Assessment and Evaluation, and Environmental Education. This conference has invited academics, researchers, teachers, practitioners, and students worldwide to participate and exchange ideas, experiences, and research findings in the field of education to make a better, more efficient, and impactful teaching and learning. This conference was attended by 190 participants and 160 presenters. Four keynote papers were delivered at the conference; the first two papers were delivered by Prof Emeritus Stephen D. Krashen from the University of Southern California, the USA and Prof Dr Bujang Rahman, M.Si. from Universitas Lampung, Indonesia. The second two papers were presented by Prof Dr Habil Andrea Bencsik from the University of Pannonia, Hungary and Dr Hisham bin Dzakiria from Universiti Utara Malaysia, Malaysia. In addition, a total of 160 papers were also presented by registered presenters in the parallel sessions of the conference. The conference represents the efforts of many individuals. Coordination with the steering chairs was essential for the success of the conference. We sincerely appreciate their constant support and guidance. We would also like to express our gratitude to the organising committee members for putting much effort into ensuring the success of the day-to-day operation of the conference and the reviewers for their hard work in reviewing submissions. We also thank the four invited keynote speakers for sharing their insights. Finally, the conference would not be possible without the excellent papers contributed by authors. We thank all authors for their contributions and participation in the 2nd ICOPE 2020. We strongly believe that the 2nd ICOPE 2020 has provided a good forum for academics, researchers, teachers, practitioners, and students to address all aspects of education-related issues in the current educational situation. We feel honoured to serve the best recent scientific knowledge and development in education and hope that these proceedings will furnish scholars from all over the world with an excellent reference book. We also expect that the future ICOPE conference will be more successful and stimulating. Finally, it was with great pleasure that we had the opportunity to host such a conference. |
| cell cycle regulation pogil: Anatomy and Physiology Patrick J.P. Brown, 2015-08-10 Students Learn when they are actively engaged and thinking in class. The activities in this book are the primary classroom materials for teaching Anatomy and Physiology, sing the POGIL method. The result is an I can do this attitude, increased retention, and a feeling of ownership over the material. |
| cell cycle regulation pogil: Foundations of Biochemistry Jenny Loertscher, Vicky Minderhout, 2010-08-01 |
| cell cycle regulation pogil: The Language of Science Education William F. McComas, 2013-12-30 The Language of Science Education: An Expanded Glossary of Key Terms and Concepts in Science Teaching and Learning is written expressly for science education professionals and students of science education to provide the foundation for a shared vocabulary of the field of science teaching and learning. Science education is a part of education studies but has developed a unique vocabulary that is occasionally at odds with the ways some terms are commonly used both in the field of education and in general conversation. Therefore, understanding the specific way that terms are used within science education is vital for those who wish to understand the existing literature or make contributions to it. The Language of Science Education provides definitions for 100 unique terms, but when considering the related terms that are also defined as they relate to the targeted words, almost 150 words are represented in the book. For instance, “laboratory instruction” is accompanied by definitions for openness, wet lab, dry lab, virtual lab and cookbook lab. Each key term is defined both with a short entry designed to provide immediate access following by a more extensive discussion, with extensive references and examples where appropriate. Experienced readers will recognize the majority of terms included, but the developing discipline of science education demands the consideration of new words. For example, the term blended science is offered as a better descriptor for interdisciplinary science and make a distinction between project-based and problem-based instruction. Even a definition for science education is included. The Language of Science Education is designed as a reference book but many readers may find it useful and enlightening to read it as if it were a series of very short stories. |
| cell cycle regulation pogil: Discipline-Based Education Research National Research Council, Division of Behavioral and Social Sciences and Education, Board on Science Education, Committee on the Status, Contributions, and Future Directions of Discipline-Based Education Research, 2012-08-27 The National Science Foundation funded a synthesis study on the status, contributions, and future direction of discipline-based education research (DBER) in physics, biological sciences, geosciences, and chemistry. DBER combines knowledge of teaching and learning with deep knowledge of discipline-specific science content. It describes the discipline-specific difficulties learners face and the specialized intellectual and instructional resources that can facilitate student understanding. Discipline-Based Education Research is based on a 30-month study built on two workshops held in 2008 to explore evidence on promising practices in undergraduate science, technology, engineering, and mathematics (STEM) education. This book asks questions that are essential to advancing DBER and broadening its impact on undergraduate science teaching and learning. The book provides empirical research on undergraduate teaching and learning in the sciences, explores the extent to which this research currently influences undergraduate instruction, and identifies the intellectual and material resources required to further develop DBER. Discipline-Based Education Research provides guidance for future DBER research. In addition, the findings and recommendations of this report may invite, if not assist, post-secondary institutions to increase interest and research activity in DBER and improve its quality and usefulness across all natural science disciples, as well as guide instruction and assessment across natural science courses to improve student learning. The book brings greater focus to issues of student attrition in the natural sciences that are related to the quality of instruction. Discipline-Based Education Research will be of interest to educators, policy makers, researchers, scholars, decision makers in universities, government agencies, curriculum developers, research sponsors, and education advocacy groups. |
| cell cycle regulation pogil: C, C Gerry Edwards, David Walker, 1983 |
| cell cycle regulation pogil: Photoperiodism in Plants Brian Thomas, Daphne Vince-Prue, 1996-10-17 Photoperiodism is the response to the length of the day that enables living organisms to adapt to seasonal changes in their environment as well as latitudinal variation. As such, it is one of the most significant andcomplex aspects of the interaction between plants and their environment and is a major factor controlling their growth and development. As the new and powerful technologies of molecular genetics are brought to bear on photoperiodism, it becomes particularly important to place new work in the context of the considerable amount of physiological information which already exists on the subject. This innovative book will be of interest to a wide range of plant scientists, from those interested in fundamental plant physiology and molecular biology to agronomists and crop physiologists. - Provides a self-sufficient account of all the important subjects and key literature references for photoperiodism - Includes research of the last twenty years since the publication of the First Edition - Includes details of molecular genetic techniques brought to bear on photoperiodism |
| cell cycle regulation pogil: Control of Messenger RNA Stability Joel Belasco, Joel G. Belasco, George Brawerman, 1993-04-06 This is the first comprehensive review of mRNA stability and its implications for regulation of gene expression. Written by experts in the field, Control of Messenger RNA Stability serves both as a reference for specialists in regulation of mRNA stability and as a general introduction for a broader community of scientists. Provides perspectives from both prokaryotic and eukaryotic systems Offers a timely, comprehensive review of mRNA degradation, its regulation, and its significance in the control of gene expression Discusses the mechanisms, RNA structural determinants, and cellular factors that control mRNA degradation Evaluates experimental procedures for studying mRNA degradation |
| cell cycle regulation pogil: Collaborative Learning Techniques Elizabeth F. Barkley, Claire H. Major, K. Patricia Cross, 2014-07-22 A guide to thirty-five creative assignments for pairs and groups Collaborative Learning Techniques is the bestseller that college and university faculty around the world have used to help them make the most of small group learning. A mountain of evidence shows that students who learn in small groups together exhibit higher academic achievement, motivation, and satisfaction than those who don't. Collaborative learning puts into practice the major conclusion from learning theory: that students must be actively engaged in building their own minds. In this book, the authors synthesize the relevant research and theory to support thirty-five collaborative learning activities for use in both traditional and online classrooms. This second edition reflects the changed world of higher education. New technologies have opened up endless possibilities for college teaching, but it's not always easy to use these technologies effectively. Updated to address the challenges of today's new teaching environments, including online, flipped, and large lectures, Collaborative Learning Techniques is a wonderful reference for educators who want to make the most of any course environment. This revised and expanded edition includes: Additional techniques, with an all-new chapter on using games to provide exciting, current, technologically-sophisticated curricula A section on effective online implementation for each of the thirty-five techniques Significantly expanded pedagogical rationale and updates on the latest research showing how and why collaborative learning works Examples for implementing collaborative learning techniques in a variety of learning environments, including large lecture classes and flipped classes Expanded guidance on how to solve common problems associated with group work The authors guide instructors through all aspects of group work, providing a solid grounding in what to do, how to do it, and why it is important for student learning. The detailed procedures in Collaborative Learning Techniques will help teachers make sure group activities go smoothly, no matter the size or delivery method of their classes. With practical advice on how to form student groups, assign roles, build team spirit, address unexpected problems, and evaluate and grade student participation, this new edition of the international classic makes incorporating effective group work easy. |
| cell cycle regulation pogil: The Operon Jeffrey H. Miller, William S. Reznikoff, 1980 |
| cell cycle regulation pogil: Eukaryotic Gene Expression Ajit Kumar, 2013-03-09 The recent surge of interest in recombinant DNA research is understandable considering that biologists from all disciplines, using recently developed mo lecular techniques, can now study with great precision the structure and regulation of specific genes. As a discipline, molecular biology is no longer a mere subspeciality of biology or biochemistry: it is the new biology. Current approaches to the outstanding problems in virtually all the traditional disci plines in biology are now being explored using the recombinant DNA tech nology. In this atmosphere of rapid progress, the role of information exchange and swift publication becomes quite crucial. Consequently, there has been an equally rapid proliferation of symposia volumes and review articles, apart from the explosion in popular science magazines and news media, which are always ready to simplify and sensationalize the implications of recent dis coveries, often before the scientific community has had the opportunity to fully scrutinize the developments. Since many of the recent findings in this field have practical implications, quite often the symposia in molecular biology are sponsored by private industry and are of specialized interest and in any case quite expensive for students to participate in. Given that George Wash ington University is a teaching institution, our aim in sponsoring these Annual Spring Symposia is to provide, at cost, a forum for students and experts to discuss the latest developments in selected areas of great significance in biology. Additionally, since the University is located in Washington, D. C. |
| cell cycle regulation pogil: The Carbon Cycle T. M. L. Wigley, D. S. Schimel, 2005-08-22 Reducing carbon dioxide (CO2) emissions is imperative to stabilizing our future climate. Our ability to reduce these emissions combined with an understanding of how much fossil-fuel-derived CO2 the oceans and plants can absorb is central to mitigating climate change. In The Carbon Cycle, leading scientists examine how atmospheric carbon dioxide concentrations have changed in the past and how this may affect the concentrations in the future. They look at the carbon budget and the missing sink for carbon dioxide. They offer approaches to modeling the carbon cycle, providing mathematical tools for predicting future levels of carbon dioxide. This comprehensive text incorporates findings from the recent IPCC reports. New insights, and a convergence of ideas and views across several disciplines make this book an important contribution to the global change literature. |
| cell cycle regulation pogil: Reaching Students Nancy Kober, National Research Council (U.S.). Board on Science Education, National Research Council (U.S.). Division of Behavioral and Social Sciences and Education, 2015 Reaching Students presents the best thinking to date on teaching and learning undergraduate science and engineering. Focusing on the disciplines of astronomy, biology, chemistry, engineering, geosciences, and physics, this book is an introduction to strategies to try in your classroom or institution. Concrete examples and case studies illustrate how experienced instructors and leaders have applied evidence-based approaches to address student needs, encouraged the use of effective techniques within a department or an institution, and addressed the challenges that arose along the way.--Provided by publisher. |
| cell cycle regulation pogil: Biophysical Chemistry James P. Allen, 2009-01-26 Biophysical Chemistry is an outstanding book that delivers both fundamental and complex biophysical principles, along with an excellent overview of the current biophysical research areas, in a manner that makes it accessible for mathematically and non-mathematically inclined readers. (Journal of Chemical Biology, February 2009) This text presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry. It lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined, leading them through fundamental concepts, such as a quantum mechanical description of the hydrogen atom rather than simply stating outcomes. Techniques are presented with an emphasis on learning by analyzing real data. Presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry Lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined Presents techniques with an emphasis on learning by analyzing real data Features qualitative and quantitative problems at the end of each chapter All art available for download online and on CD-ROM |
| cell cycle regulation pogil: Mechanisms of Hormone Action P Karlson, 2013-10-22 Mechanisms of Hormone Action: A NATO Advanced Study Institute focuses on the action mechanisms of hormones, including regulation of proteins, hormone actions, and biosynthesis. The selection first offers information on hormone action at the cell membrane and a new approach to the structure of polypeptides and proteins in biological systems, such as the membranes of cells. Discussions focus on the cell membrane as a possible locus for the hormone receptor; gaps in understanding of the molecular organization of the cell membrane; and a possible model of hormone action at the membrane level. The text also ponders on insulin and regulation of protein biosynthesis, including insulin and protein biosynthesis, insulin and nucleic acid metabolism, and proposal as to the mode of action of insulin in stimulating protein synthesis. The publication elaborates on the action of a neurohypophysial hormone in an elasmobranch fish; the effect of ecdysone on gene activity patterns in giant chromosomes; and action of ecdysone on RNA and protein metabolism in the blowfly, Calliphora erythrocephala. Topics include nature of the enzyme induction, ecdysone and RNA metabolism, and nature of the epidermis nuclear RNA fractions isolated by the Georgiev method. The selection is a valuable reference for readers interested in the mechanisms of hormone action. |
| cell cycle regulation pogil: The Making of the Fittest: DNA and the Ultimate Forensic Record of Evolution Sean B. Carroll, 2007-08-28 A geneticist discusses the role of DNA in the evolution of life on Earth, explaining how an analysis of DNA reveals a complete record of the events that have shaped each species and how it provides evidence of the validity of the theory of evolution. |
| cell cycle regulation pogil: The Pancreatic Beta Cell , 2014-02-20 First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. - Expertise of the contributors - Coverage of a vast array of subjects - In depth current information at the molecular to the clinical levels - Three-dimensional structures in color - Elaborate signaling pathways |
| cell cycle regulation pogil: Phys21 American Physical Society, American Association of Physics Teachers, 2016-10-14 A report by the Joint Task Force on Undergraduate Physics Programs |
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The cell cycle, the series of events that leads to cell growth and division, is a fundamental process in all living organisms. Precise regulation of this cycle is crucial for maintaining genomic …
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Model #1-‐ Cell Cycle. There are 4 phases in the cell cycle as shown in model #1. The order of the cell cycle is as follow: G1. S. G2. Mitosis. The size of the cell increase during the G1 …
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a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists. The Eukaryotic Cell Cycle J. A. Bryant,Dennis Francis,2008 Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers.
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• The distinct events of the cell cycle are directed by a distinct cell cycle control system. • These molecules trigger and coordinate key events in the cell cycle. • The control cycle has a built-in clock, but it is also regulated by external adjustments and internal controls. • A checkpoint in the cell cycle is a critical control ...
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Yet, all of the different cell types in our body are all derived, or arise, from a single cell. After all, at the beginning of life all multicellular organisms start as a single cell. As multicellular organisms grow and develop their cells specialize into one of the many cells that make up the body, such as a heart, liver, or muscle cell ...
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cell cycle and how lack of regulation can lead to cancer. Learning experiences include: • Part 1: Information gathering in the context of a young female who has been diagnosed with skin cancer. • Part 2: Exploration of a basic understanding of cancer from a historical perspective. This experience utilizes a series of four short video clips ...
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a structured framework for exploring complex topics like cell cycle regulation. # Key Concepts in Cell Cycle Regulation The cell cycle is divided into four distinct phases: G1 (Gap 1): A period of growth and preparation for DNA replication. S (Synthesis): The phase where DNA is replicated.
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The cell cycle is the life of a cell from the time it is first formed from a dividing parent cell until its own division into two daughter cells. This process is cyclical because every cell forms from a preexisting cell. 3. What is the meaning of “genome”? Compare your genome to that of a prokaryotic cell.
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21. Keeping in mind the events of each part of the cell cycle, mark with a double arrow on Model 1 where those cells might (either temporarily or permanently) exit the cell cycle to G 0. Label this as G 0. Why did you choose this location for G 0? Hint: Think of a place in the cell cycle where the cell is functioning normally, but not preparing ...
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